LAB
Stark Neuroscience Research Center
Indiana University School of Medicine
Deng
Publications
Recent Works
Differential effects of exercise and hormone treatment on spinal cord injury-induced changes in micturition and morphology of external urethral sphincter motoneurons
Hibbard EA, Du X, Zhang Y, Xu XM, Deng L, Sengelaub DR. Differential effects of exercise and hormone treatment on spinal cord injury-induced changes in micturition and morphology of external urethral sphincter motoneurons. Restor Neurol Neurosci. 2024
Regeneration of Propriospinal Axons in Rat Transected Spinal Cord Injury through a Growth-Promoting Pathway Constructed by Schwann Cells Overexpressing GDNF
Du X, Zhang S, Khabbaz A, Cohen KL, Zhang Y, Chakraborty S, Smith GM, Wang H, Yadav AP, Liu N, Deng L. Regeneration of Propriospinal Axons in Rat Transected Spinal Cord Injury through a Growth-Promoting Pathway Constructed by Schwann Cells Overexpressing GDNF. Cells. 2024.
Locomotor Exercise Enhances Supraspinal Control of Lower-Urinary-Tract Activity to Improve Micturition Function after Contusive Spinal-Cord Injury
Deng L, Sui T, Wang DV, Hou S, Cao X, Peng K, Xu Z, Xu X. Locomotor exercise enhances supraspinal control of lower-urinary-tract activity to improve micturition function after contusive spinal-cord injury. Cells. 2022.
Laminin-coated multifilament entubulation, combined with Schwann cells and glial cell line-derived neurotrophic factor, promotes unidirectional axonal regeneration in a rat model of thoracic spinal cord hemisection
Deng LX, Liu NK, Wen RN, Yang SN, Wen X, Xu XM. Laminin-coated multifilament entubulation, combined with Schwann cells and glial cell line-derived neurotrophic factor, promotes unidirectional axonal regeneration in a rat model of thoracic spinal cord hemisection. Neural regeneration research. 2021.
Other Publications
Deng L, Ravenscraft B, Xu XM. Exploring propriospinal neuron-mediated neural circuit plasticity using recombinant viruses after spinal cord injury. Exp Neurol. 2022 Mar;349:113962. doi: 10.1016/j.expneurol.2021.113962. Epub 2021 Dec 22. PMID: 34953895.
Monje PV, Deng L, Xu XM. Human Schwann Cell Transplantation for Spinal Cord Injury: Prospects and Challenges in Translational Medicine. Front Cell Neurosci. 2021 Jun 18;15:690894. doi: 10.3389/fncel.2021.690894. PMID: 34220455; PMCID: PMC8249939.
Deng L, Ruan Y, Chen C, Frye CC, Xiong W, Jin X, Jones K, Sengelaub D, Xu XM. Characterization of dendritic morphology and neurotransmitter phenotype of thoracic descending propriospinal neurons after complete spinal cord transection and GDNF treatment. Exp Neurol. 2016 Mar;277:103-114. doi: 10.1016/j.expneurol.2015.12.018. Epub 2015 Dec 28. PMID: 26730519; PMCID: PMC4761305.
Deng LX, Walker Chandler, Xu XM, Schwann Cell-Mediated Axonal Regeneration in the Central Nervous System, Book “Neuronal regeneration”, Chapter , 2015, Academic Press, Pages 337-349,
Deng LX, Walker C, Xu XM. Schwann cell transplantation and descending propriospinal regeneration after spinal cord injury. Brain Res. 2015 Sep 4;1619:104-14. doi: 10.1016/j.brainres.2014.09.038. Epub 2014 Sep 26. PMID: 25257034; PMCID: PMC4375094.
Deng LX, Deng P, Ruan Y, Xu ZC, Liu NK, Wen X, Smith GM, Xu XM. A novel growth-promoting pathway formed by GDNF-overexpressing Schwann cells promotes propriospinal axonal regeneration, synapse formation, and partial recovery of function after spinal cord injury. J Neurosci. 2013 Mar 27;33(13):5655-67. doi: 10.1523/JNEUROSCI.2973-12.2013. PMID: 23536080; PMCID: PMC3664932.
Deng LX, Hu J, Liu N, Wang X, Smith GM, Wen X, Xu XM. GDNF modifies reactive astrogliosis allowing robust axonal regeneration through Schwann cell-seeded guidance channels after spinal cord injury. Exp Neurol. 2011 Jun;229(2):238-50. doi: 10.1016/j.expneurol.2011.02.001. Epub 2011 Feb 21. PMID: 21316362; PMCID: PMC3100372. (Cover paper)